0704-883-0675     |      dataprojectng@gmail.com

EVALUATION OF TABLETING PROPERTIES OF CRUDE TURMERIC (CURCUMA LONGA LINN) POWDER

  • Project Research
  • 1-5 Chapters
  • Abstract : Available
  • Table of Content: Available
  • Reference Style: APA
  • Recommended for : Student Researchers
  • NGN 5000

ABSTRACT

The aim of this work is to formulate crude turmeric powder into tablet form. The powder was produced from the turmeric rhizome. Physicochemical properties of the powder; angle of repose (AR), bulk density (BD), tapped density (TD), Hausner‟s ratio (HR), Carr‟s index (CI), true density, moisture content, and flow rate (FR) were evaluated. The particles size and morphology were determined using Scanning electron microscope and sieve analysis. The tablets were formulated using both wet granulation and direct compression methods. The wet granulation was carried out using microcrystalline cellulose (MCC) as diluent and gelatin (GLT) as binder and compared with maize starch (MS), polyvinylpyrrolidone (PVP), and Acacia (AC) as binders. Direct compression method was carried out using Avicel PH101 and Ludipress. Compaction studies were also conducted on the powder. The powder particles were found to be rough, elongated and flaky shaped, with poor flow based on AR (40.3⁰), HR (1.736), CI (42.4 %) and FR (1.4 g/s) and the particles are also interlocked. The granules exhibited marked improvement in flowability: AR (31.14 ° - 34.79 °), HR (1.21-1.29), CI (17.14 – 37.00), FR (1.44 – 2.81 g/s) and moisture content (10.50 – 13.50 %). The powder deformed by fragmentation and is brittle in nature. The granules have improved plastic deformation explained by both Heckel and Kawakita equations. Turmeric tablets with good mechanical properties were produced by both wet granulation and direct compression methods. Gelatin binder produced good tablets at 2.5 % concentrations and above. Using wet granulation method, MS at 5 % binder concentration produced best tablets in terms of mechanical strength (CSFR: 8.667 compared with gelatin‟s 7.547) but 5 % gelatin binder gave best release tablets (97.70 % at 45 min). Avicel PH101 and Ludipress produced good tablets both at 50 – 60 % dilutions. Avicel viii PH101 produced best quality tablets in terms of mechanical strength (CSFR/DT: 6.1460 compared with Ludipress: 2.587) and release profile (86.19 % at 45 min). Turmeric powder can best be formulated into tablet by wet granulation method using gelatin as a binder while Avicel PH101 produced best tablets by direct compression method.




FIND OTHER RELATED TOPICS


Related Project Materials

An evaluation of nurses' adherence to standard guidelines for intramuscular injections at Cross River State Teaching Hospital

Background of the study

Intramuscular (IM) injections are one of the most common methods of administering medications in...

Read more
IMPACT OF PUBLIC RELATIONS ON A CORPORATE ORGANISATION (A STUDY OF FIRST BANK OF NIGERIA PLC ENUGU ZONAL HEADQUARTERS)

Abstract

This work is aimed at looking into the impact of public relations in First Bank of Nigeria PLC Enugu Zonal Headquarters. First B...

Read more
A Study on the Effect of Income Growth on Business Investment in Nigeria

Background of the Study
Income growth is widely regarded as a crucial determinant of business investment decisions. In Nig...

Read more
The Impact of Solar Energy Adoption on Rural Business Growth in Sabon Gari Local Government Area, Kaduna State

Background of the Study

The adoption of renewable energy, particularly solar energy, has become an esse...

Read more
A study of interactive email marketing on boosting click-through rates: Evidence from a subscription service in Kano, Nigeria

Background of the study
Interactive email marketing is an emerging strategy that utilizes engaging elements such as embedde...

Read more
A study on the use of artificial intelligence in patient triage systems: A study of hospitals in Kaduna State

Background of the Study
Artificial intelligence (AI) is increasingly being incorporated into various aspects of healthcare,...

Read more
THE PROBLEMS OF LOCAL GOVERNMENT AUTONOMY AND ITS IMPLICATIONS IN THE EFFECTIVE MANAGEMENT OF PRIMARY SCHOOLS

Background of the Study

In the world over, education has become an essential commodity that determines...

Read more
The Influence of Financial Reporting Quality on Shareholder Value: A Study of Fidelity Bank in Bauchi State

Financial reporting is a critical component of corporate governance and transparency. It provides shareholders, investors, and other stakeholders w...

Read more
The impact of socio-economic status on HIV/AIDS prevalence in Katsina State

Background of the Study
Socio-economic status (SES) is a critical determinant of health, influencing exposure to risk facto...

Read more
An Examination of Sales Promotion Strategies in Nigerian Supermarkets: A Case Study of Shoprite, Abuja

Background of the Study

Sales promotion strategies are essential marketing tools used to stimulate consumer interest, enhance product vis...

Read more
Share this page with your friends




whatsapp