0704-883-0675     |      dataprojectng@gmail.com

EVALUATION OF TABLETING PROPERTIES OF CRUDE TURMERIC (CURCUMA LONGA LINN) POWDER

  • Project Research
  • 1-5 Chapters
  • Abstract : Available
  • Table of Content: Available
  • Reference Style: APA
  • Recommended for : Student Researchers
  • NGN 5000

ABSTRACT

The aim of this work is to formulate crude turmeric powder into tablet form. The powder was produced from the turmeric rhizome. Physicochemical properties of the powder; angle of repose (AR), bulk density (BD), tapped density (TD), Hausner‟s ratio (HR), Carr‟s index (CI), true density, moisture content, and flow rate (FR) were evaluated. The particles size and morphology were determined using Scanning electron microscope and sieve analysis. The tablets were formulated using both wet granulation and direct compression methods. The wet granulation was carried out using microcrystalline cellulose (MCC) as diluent and gelatin (GLT) as binder and compared with maize starch (MS), polyvinylpyrrolidone (PVP), and Acacia (AC) as binders. Direct compression method was carried out using Avicel PH101 and Ludipress. Compaction studies were also conducted on the powder. The powder particles were found to be rough, elongated and flaky shaped, with poor flow based on AR (40.3⁰), HR (1.736), CI (42.4 %) and FR (1.4 g/s) and the particles are also interlocked. The granules exhibited marked improvement in flowability: AR (31.14 ° - 34.79 °), HR (1.21-1.29), CI (17.14 – 37.00), FR (1.44 – 2.81 g/s) and moisture content (10.50 – 13.50 %). The powder deformed by fragmentation and is brittle in nature. The granules have improved plastic deformation explained by both Heckel and Kawakita equations. Turmeric tablets with good mechanical properties were produced by both wet granulation and direct compression methods. Gelatin binder produced good tablets at 2.5 % concentrations and above. Using wet granulation method, MS at 5 % binder concentration produced best tablets in terms of mechanical strength (CSFR: 8.667 compared with gelatin‟s 7.547) but 5 % gelatin binder gave best release tablets (97.70 % at 45 min). Avicel PH101 and Ludipress produced good tablets both at 50 – 60 % dilutions. Avicel viii PH101 produced best quality tablets in terms of mechanical strength (CSFR/DT: 6.1460 compared with Ludipress: 2.587) and release profile (86.19 % at 45 min). Turmeric powder can best be formulated into tablet by wet granulation method using gelatin as a binder while Avicel PH101 produced best tablets by direct compression method.




FIND OTHER RELATED TOPICS


Related Project Materials

CARD READER AS A TOOL FOR ELECTION TRANSPARENCY (2015 ELECTION)

1 BACKGROUND OF STUDY

The electoral process in Nigeria has gain a lot of transparency since the inception of the use of...

Read more
An Assessment of the Enforcement of Freedom of Association in Labor Unions: A Study of Jalingo Local Government Area, Taraba State

Chapter One: Introduction

1.1 Background of the Study
The freedom of association is a fundamenta...

Read more
The Impact of IFRS on Tax Revenue Reporting in Nigeria

Background of the Study

The adoption of International Financial Reporting Standards (IFRS) in Nigeria, as in many other...

Read more
The Effect of FDI Inflows on Job Creation in Nigeria’s Manufacturing Sector

Background of the Study
The manufacturing sector in Nigeria has long been considered a potential engine for industrializati...

Read more
SOCIOECONOMIC IMPLICATIONS OF FAMILY SIZE ON CHILDREN’S WELFARE AMONG ROAD TRANSPORT EMPLOYEES IN ALIMOSHO LGA, LAGOS STATE

Background Of The

AN INVESTIGATION INTO THE CAUSES AND PREVENTION OF COVID-19 AMONG ALVAN IKOKU FEDERAL COLLEGE OF EDUCATION, OWERRI

ABSTRACT

This study was carried out to empirically investigate into the causes and prevention of Covid-...

Read more
An appraisal of geopolitical pressures on forest conservation in Rano Local Government Area, Kano State

Background of the Study
Rano Local Government Area (LGA) in Kano State has experienced significant pressures on its forest resources due to...

Read more
THE ROLE OF BROADCASTING IN THE RURAL DEVELOPMENT

Abstract

Rural development of my kind in any place can only be meaningfully achieved through a well – planned and...

Read more
An investigation of AI-driven personalization on consumer engagement: A study of a tech company in Kaduna, Nigeria

Background of the Study:

AI-driven personalization uses artificial intelligence to tailor digital content and marketing messages based on...

Read more
An Evaluation of Remote Work and Stress Levels Among IT Professionals in Taraba State

Background of the Study

Remote work has become a prevalent work arrangement, especially in the IT sector, where employees can perform tas...

Read more
Share this page with your friends




whatsapp